Alzental 400mg

Indications

• Pork tapeworm (Taenia solium) in the neurocysticercosis (in or out parenchymal neurocysticercosis).
• For the treatment of cystic hydatid disease of the liver, lung and peritoneum caused by the larval form of the dog tapeworm (Echinococcus granulosus) before operable or inoperable.
• Single or mixed infections caused by intestinal parasites, such as Ascaris lumbricoides, Ancylostoma duodenale and Necator americanus, Trichuris trichiura, Strongyloides stercoralis, Enterobius vermicularis and Mansonella perstants, Wuchereria bancrofti, Loa loa.
• Cutaneous larva migrant or visceral larva migrans caused by Toxocara canis or cati.
• Giardiasis caused by Giardia.
• Trematode infections caused by Clonorchis sinensis.

Contraindications

• Patients with a history of hypersensitivity to the compounds of benzimidazole class or any components of the drug.
• Pregnant women.

Compositon/Ingredients

Dosage and administration

• Pork tapeworm: Weighing ³ 60 kg: 400 mg given twice daily with meals for 8 – 30 days. Weighing < 60 kg: 15 mg/kg daily (not more than 800 mg daily), in 2 divided doses with meals, for 8 – 30 days. Dose may be repeated, if needed. Children < 6 years: Not doses.
• Dog tapeworm: Dose ditto, in three 28 days courses of therapy, separated by two 14 days albendazole free intervals.
• Ascaris lumbricoides, Ancylostoma duodenale or Trichuris trichiura Enterobius vermicularis: A single dose of 400 mg (Children under 2 years: 200 mg). Doses may be repeated after 3 weeks.
• Strongyloidiasis: 400 mg (Children under 2 years: 200 mg) daily in a single dose for 3 days. Doses may be repeated after 3 weeks.
• Capillariasis: 200 mg given twice daily for 10 days.
• Cutaneous larva migrans: 400 mg daily in a single dose by mouth for 3 days. Treatment for 5 – 7 days may be more effective. Children: 5 mg/kg daily in a single dose by mouth for 3 days.
• Giardia: 400 mg daily in a single dose by mouth for 5 days.
• Clonorchis sinensis: 10 mg/kg daily in a single dose by mouth for 7 days.
• Lymphatic filariasis, potential filariasis infection: A single dose of albendazole 400 mg and diethylcarbamazine 6 mg/kg or ivermectin (200 mg/kg) effective in preventing disease transmission. These doses are given once each year for at least 5 years.
• Visceral larva migrans: 400 mg given twice daily for 5 days.

Precaution

• Ophthalmic exams should be performed before initiating therapy for pork tapeworm in the parenchymal neurocysticercosis to rule out intraocular cysts.
• Hepatic dysfunction patients.
• Nursing women.
• For women of childbearing age, albendazole should be used within the first 7 days of the menstrual cycle. Use contraception during and after stopping the drug 1 month.
• Patients should be aware of how they react to Alzental 400 before driving or operating machinery (cause headache, vertigo).

Storage

Store at temperature below 30°C, protect from light.