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Hagimox 500mg (10 blisters x 10 capsules/box)
Brand: DHG PharmaProduct Code: A528020579

Hagimox 500mg (10 blisters x 10 capsules/box)

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Hagimox 500mg contains the active ingredient amoxicillin which is a penicillin antibiotic. Amoxicillin is an aminopenicillin, stable in gastric acid, has a broader spectrum of activity than benzylpenicillin, particularly against Gram-negative bacilli. The bactericidal effect of amoxicillin is by interfering with the biosynthesis of the bacterial cell wall mucopeptide. Amoxicillin is active against most of Gram-positive and Gram-negative microorganisms: Streptococci, non-penicillinase producing Staphylococci, H. influenzae, Diplococcus pneumoniae, N. gonorrheae, E. coli and Proteus mirabilis. Amoxicillin is not active against penicillinase-producing strains, especially to methicillin-resistant Staphylococci, all strains of Pseudomonas and most of Klebsiella and Enterobacter strains. Amoxicillin has been reported to be more active in vitro than ampicillin against Enterococcus faecalis and Salmonella spp. but less active against Shigella spp.. The spectrum of activity of amoxicillin may be extended by the concomitant use of sulbactam and clavulanic acid. Amoxicillin combined with clavulanic acid (16.8%) is reported to be resistant to E. coli.

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Indications

Upper respiratory tract infections.
Lower respiratory tract infections due to streptococci, pneumococci, non-penicillinase-producing staphylococci and H. influenzae.
Uncomplicated urinary tract infections.
Gonorrhoea.
Biliary tract infections.
Skin and muscle infections due to streptococci, staphylococci, E. coli sensitive to amoxicillin.


Contraindications

A known history of hypersensitivity to any penicillins.


Compositon/Ingredients

Amoxicilin 500mg

Dosage and administration

The drug can be taken before or after meals.
Adults and children > 10 years of age: 500 mg (1 capsule) x 3 times daily.
For patients suffered from renal impairment, the dose is as follows:
CrCl < 10 ml/ min: 500 mg/ 24 hrs.
CrCl > 10 ml/ min: 500 mg/ 12 hrs.


Precaution

Renal and hepatic functions should be periodically observed in case of long-term administration. A severe hypersensitive reaction may occur in patients with a history of allergy to penicillin or other allergens, so their history of allergy should be observed carefully before initiating therapy with amoxicillin.
In case the allergic reactions e.g erythema, Quincke’s oedema, anaphylactic shock, Stevens-Johnson syndrome occur, the therapy with amoxicillin should be stopped and first-aid treatment with adrenaline, breathing of oxygen, intravenous injection of corticosteroid, ventilation including intubation should be applied and never using penicillin or cephalosporin any more.


Storage

Store at temperature below 30°C, protect from light.

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Hagimox 500mg (10 blisters x 10 capsules/box)

Hagimox 500mg (10 blisters x 10 capsules/box)

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