Spirastad 1.5 M.I.U (3 blisters x 10 tablets/box)

Indications

Infectious conditions in respiratory, cutaneous and genital tracts caused by sensitive organisms. Prophylaxis of meningitis caused by Meningococci in patients with contraindication to rifampicin. Prevention of congenital toxoplasmosis during pregnancy. Chemoprophylaxis of recurrent acute rheumatic arthritis in patients allergic to penicillins.

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Contraindications

Patients with known hypersensitivity to spiramycin, erythromycin or to any ingredient in the formulation.

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Compositon/Ingredients

Spiramycin 1.500.000 IU

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Dosage and administration

Adults: 5 million – 3 million IU, 3 times daily. Infants and children: 150 thousand IU/kg daily, in 3 divided doses. Prophylaxis of meningitis due to Meningococci: Adults: 3 million IU every 12 hours. Children: 75 thousand IU/kg every 12 hours for 5 days. Prevention of congenital toxoplasmosis during pregnancy: 9 million IU daily in divided doses for 3 weeks, repeated 2-weekly intervals. Combination or alternation with a pyrimethamine/sulfonamide regimen may improve results.

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Precaution

Spiramycin should be used cautiously in patients with hepatic dysfunction; pregnant women. Mothers should discontinue breast feeding during spiramycin administration.

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Storage

Store at temperature below 30°C, protect from light.