Indications
Pork tapeworm (Taenia solium) in the neurocysticercosis (in or out parenchymal neurocysticercosis).
For the treatment of cystic hydatid disease of the liver, lung and peritoneum caused by the larval form of the dog tapeworm (Echinococcus granulosus) before operable or inoperable.
Single or mixed infections caused by intestinal parasites, such as Ascaris lumbricoides, Ancylostoma duodenale and Necator americanus, Trichuris trichiura, Strongyloides stercoralis, Enterobius vermicularis and Mansonella perstants, Wuchereria bancrofti, Loa loa.
Cutaneous larva migrant or visceral larva migrans caused by Toxocara canis or cati.
Giardiasis caused by Giardia
Trematode infections caused by Clonorchis sinensis.
Contraindications
Patients with a history of hypersensitivity to the compounds of benzimidazole class or any components of the drug.
Pregnant women.
Compositon/Ingredients
Albendazole 400mg
Dosage and administration
Pork tapeworm: Weighing ³ 60 kg: 400 mg given twice daily with meals for 8 – 30 days. Weighing < 60 kg: 15 mg/kg daily (£ 800 mg daily), in 2 divided doses with meals, for 8 – 30 days. Dose may be repeated, if needed. Children < 6 years: Not doses.
Dog tapeworm: Dose ditto, in three 28 days courses of therapy, separated by two 14 days albendazole free intervals.
Ascaris lumbricoides, Ancylostoma duodenale or Trichuris trichiura Enterobius vermicularis: A single dose of 400 mg (Children £ 2 years: 200 mg). Doses may be repeated after 3 weeks.
Strongyloidiasis: 400 mg (Children £ 2 years: 200 mg) daily in a single dose for 3 days. Doses may be repeated after 3 weeks.
Capillariasis: 200 mg given twice daily for 10 days.
Cutaneous larva migrans: 400 mg daily in a single dose by mouth for 3 days. Treatment for 5 – 7 days may be more effective. Children: 5 mg/kg daily in a single dose by mouth for 3 days.
Giardia: 400 mg daily in a single dose by mouth for 5 days.
Clonorchis sinensis: 10 mg/kg daily in a single dose by mouth for 7 days.
Lymphatic filariasis, potential filariasis infection: A single dose of albendazole 400 mg and diethylcarbamazine 6 mg/kg or ivermectin (200 mg/kg) effective in preventing disease transmission. These doses are given once each year for at least 5 years.
Visceral larva migrans: 400 mg given twice daily for 5 days.
Precaution
Ophthalmic exams should be performed before initiating therapy for pork tapeworm in the parenchymal neurocysticercosis to rule out intraocular cysts.
Hepatic dysfunction patients.
Nursing women.
For women of childbearing age, albendazole should be used within the first 7 days of the menstrual cycle. Use contraception during and after stopping the drug 1 month.
Patients should be aware of how they react to Hyaron 400 before driving or operating machinery (cause headache, vertigo).
Storage
Store at temperature below 30°C, protect from light.
